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Objective: To compare left ventricular myocardial mechanics detected by cardiac magnetic resonance tissue tracking(CMR-TT) between patients with constrictive pericarditis(CP) and restrictive cardiomyopathy(RCM),and see if those can be used to differentiate CP from RCM patients. Methods: A total of 23 patients with CP, 20 patients with RCM, who hospitalized in Beijing Anzhen Hospital from January 2014 to April 2019 were included in this study and 25 healthy subjects served as control group, all subjects underwent cardiac magnetic resonance examination. Myocardial mechanics were evaluated by 2-dimensional(2D) and 3-dimensional(3D) CMR-TT in terms of global longitudinal strain(GLS), circumferential strain(GCS), radial strain(GRS) and the lateral wall strain to septal wall strain ratio(lateral/septal ratio) of basal, mid-cavity and apical. The diagnostic area under the receiver operating characteristic curve (ROC) was evaluated for differentiating CP from RCM. Results: Age, sex and heart rate were similar between CP and RCM patients(all P>0.05). 2D-GLS, 3D-GLS, GCS and GRS in CP and RCM groups were significantly lower than those in normal control group(all P<0.05).3D-GLS value was significantly lower in RCM patients than in CP patients(P<0.05), the area under the curve (AUC)=0.787(sensitivity 80%, specificity 78%). 3D-GCS was significantly lower in CP group than in RCM group(P<0.05), the AUC=0.737(sensitivity 80%, specificity 65%). However, there was no significant difference between CP and RCM in 3D-GRS(P>0.05). Compared with RCM, the circumferential and radial lateral/septal ratios of the basal were significantly lower in CP group than in RCM group(both P<0.05), AUC=0.737(sensitivity 70%, specificity 83%) and 0.737 (sensitivity 60%, specificity 87%), respectively. The left ventricular myocardial mechanics strain curve of the CP,RCM and normal control were different. The CP patients presented as " rapidly down-a platform" form, the RCM presented as "slowly down" form, and normal control presented as "rapidly down" form. Conclusion: Evaluating the differences in the diastolic process of left ventricular myocardium and left ventricular myocardial mechanics strain curve is helpful to differentiate CP from RCM patients.
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Humans , Cardiomyopathy, Restrictive , Magnetic Resonance Spectroscopy , Myocardium , Pericarditis, Constrictive , Reproducibility of Results , Ventricular Function, LeftABSTRACT
Objective To study the impact of heartbeat on the left ventricular myocardial (mLV) and the left anterior descending (LAD) coronary arterial dosimetry following intensity modulated radiotherapy (IMRT) for left-sided breast carcinoma.Methods A total of 15 female patients who received electrocardiography gated 4D-CT scan in inspiratory breathing-holding were enrolled.According to cardiac cycle,20 time-phase images were reconstructed from 0 to 95％ at 5％ interval.Then,the mLV and the LAD were delineated respectively and the IMRT plans of the left breast carcinoma were generated based on 0％ phase CT images.The volume and dice similarity coefficient (DSC) of the mLV were calculated,and the variation range of the mLV and the LAD dose-volume indexes were compared among different phases.Results The average rate of DSC variation of mLV was eightfold of volume,which reached to 472.07％,and the average change rate of mLV (Dmean) was up to 41.95％.The difference of the mLV's volume and DSC was statistically significant between the maximum and minimum(t =-6.585,-28.870,P＜0.05),as well as the D V10,V20,V30 and V40(t=-5.260,-4.084,-3.592,-3.273,-2.566,P ＜0.05).The average change rate of the LAD's D was up to 130.14％.The difference of D V10,V20,V30 and V40 of LAD was statistically significant between the maximum and minimum(t =-9.758,-8.810,-8.682,-7.853,-6.205,P ＜ 0.05).Conclusions The dosimetry impact of heartbeat on mLV and LAD should not be ignored.
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Prediction of potential performance is one of the goals of exercise physiology investigations. When Selecting a horse for competition, one of the main objectives is to choose the one that predictably will reveal a competitive aptitude above the average. The horses used in this study underwent a two-dimensional echocardiography study and a conventional 3 leads electrocardiogram. The results show that heart score is not an appropriate index to evaluate the heart size in the horse. On the other hand, there are currently more suitable and accurate procedures such as echocardiography that allow performing a clear anatomical evaluation and accurate measurement in order to calculate LVMM and to predict performance.